It is a personal preference on which to use. But also, if you prefer trolling slower speeds, crawler harnesses, bouncers/inlines. IMHO, inline boards are a much better tool to get the job done. As far as running more lines with big boards. Yes if you typically run 16-22 lines, go big boards and use jets, slide diver as a diving controller. If you fish with someone who is experienced with inline boards, running 10 boards/5 per side is pretty easy. I've done more, but folks getting ahold of the correct rod with a fish on can become a problem. It is easier using rod trees to run that many, but not required. And you can reset any board at any time when set up properly. Typically when running inline boards, there will also be 2 downrods/bouncers no boards which takes the total to 12 lines when using 10 inline boards.